Loss aversion, the principle that losses have a greater impact on decision-making than gains, can be modulated by stress. Most findings reported that stress reduces loss aversion, in line with the alignment hypothesis. Yet, decision-making was always assessed at the early stages of the stress response. Instead, the latter phase of the stress response enhances the salience-network and then, it could amplify the salience of losses, thereby increasing loss aversion. To our knowledge, it has never been studied how the latter stress response influences loss aversion and our aim is to fill this gap. 92 participants were divided into experimental and control group. The first one was exposed to the Trier Social Stress Test, and controls viewed a match-length distractor video. Both groups performed a mixed gamble task to measure loss aversion through a Bayesian-computational model. During and after the stressor, experimental group exhibited signs of both physiological and psychological stress which indicated that stress induction was effective. However, rather than increasing, loss aversion of stressed participants was lower. These results constitute a new evidence of stress influencing loss aversion and are discussed within the alignment hypothesis, according to which stress aligns sensitivity to gains and losses.