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Chitosans: Uses and applications in pharmaceutical technology

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Chitosans: Uses and applications in pharmaceutical technology

dc.contributor.author	Zornoza Sabina, Teodoro
dc.contributor.author	Cano Cebrián, María José
dc.contributor.author	Granero Maciá, Luis
dc.contributor.author	Polache Vengut, Ana
dc.date.accessioned	2023-11-20T10:41:15Z
dc.date.available	2023-11-20T10:41:15Z
dc.date.issued	2002
dc.identifier.uri	https://hdl.handle.net/10550/91254
dc.description.abstract	The multiple pharmaceutical applications of chitosans have been reviewed in this paper. After describing its structure and physico-chemical properties, an overview of the use of this polymer in controlled release dosage forms as well as in other dosage forms to improve bioavailability and safety has been made. Furthermore, the capacity of chitosan to promote the intestinal and nasal absorption is analyzed including the discussion of the mechanisms of action. The authors also outline the newer applications of chitosans such as in antitumor therapy, vaccines delivery, gene therapy and cellular transplant. Finally, the safety of this polymer is reviewed putting in evidence its low toxicity and biocompatibility which make chitosan an exciting and promising excipient for the pharmaceutical industry for present and future applications.
dc.language.iso	spa
dc.relation.ispartof	Ciencia y Tecnología Pharmaceutica, 2002, vol. 12, num. 4, p. 180-189
dc.source	Zornoza Sabina, Teodoro Cano Cebrián, María José Granero Maciá, Luis Polache Vengut, Ana 2002 Chitosans: Uses and applications in pharmaceutical technology Ciencia y Tecnología Pharmaceutica 12 4 180 189
dc.subject	Tecnologia farmacèutica
dc.subject	Farmacologia
dc.subject	Farmàcia
dc.title	Chitosans: Uses and applications in pharmaceutical technology
dc.type	journal article
dc.date.updated	2023-11-20T10:41:16Z
dc.identifier.idgrec	031616
dc.rights.accessRights	open access