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Frailty and Sarcopenia in Acute-on-Chronic Liver Failure

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Frailty and Sarcopenia in Acute-on-Chronic Liver Failure

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dc.contributor.author Puchades, Lorena
dc.contributor.author Herreras, Julia
dc.contributor.author Cebrià i Iranzo, Maria dels Àngels
dc.contributor.author Cezón Serrano, Natalia
dc.contributor.author Di Maira, Tommaso
dc.contributor.author Berenguer Haym, Marina
dc.date.accessioned 2023-11-21T13:42:51Z
dc.date.available 2023-11-21T13:42:51Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/10550/91287
dc.description.abstract In patients with cirrhosis, sarcopenia is a critical reduction in skeletal muscle mass and frailty represents a status of global physical dysfunction caused by under nutrition, muscle wasting, and functional impairment. Both are prevalent conditions in liver transplant candidates and have shown to be independent predictors of adverse outcome. Evidence supports their incorporation into clinical practice both as a prognostic factor guiding clinical decision making and as a tool to identify candidates for physical and nutritional interventions. The wide heterogeneity of instruments used for sarcopenia and frailty measurement, the absence of a single suitable instrument for sarcopenia and frailty assessment in the outpatient versus inpatient acute- on-chronic clinical scenario, and the lack of strong evidence showing a beneficial effect of sarcopenia and frailty improvement on outcomes before and after transplantation are some of the questions that remain unanswered
dc.language.iso eng
dc.relation.ispartof Hepatology Communications, 2021, vol. 5, num. 8, p. 1333-1347
dc.source Puchades, Lorena, Herreras, Julia, Cebrià i Iranzo, Maria dels Àngels, Cezón Serrano, Natalia, Di Maira, Tommaso, Berenguer Haym, Marina (2021). Frailty and Sarcopenia in Acute-on-Chronic Liver Failure. Hepatology Communications, 5 8 1333 1347. https://doi.org/10.1002/hep4.1722
dc.subject Patologia
dc.subject Malalties
dc.title Frailty and Sarcopenia in Acute-on-Chronic Liver Failure
dc.type journal article
dc.date.updated 2023-11-21T13:42:51Z
dc.identifier.doi 10.1002/hep4.1722
dc.identifier.idgrec 144286
dc.rights.accessRights open access

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