NAGIOS: RODERIC FUNCIONANDO

Synthesis and application of new iminopyridine ligands in the enantioselective palladium-catalyzed allylic alkylation

Repositori DSpace/Manakin

Valencià Castellano

Inici
Investigació
e-prints
23 - Química
Visualitza element

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Synthesis and application of new iminopyridine ligands in the enantioselective palladium-catalyzed allylic alkylation

Mostra el registre complet de l'element

Visualització (426.0Kb)

Solinas, Maurizio; Sechi, Barbara; Chelucci, Giorgio; Baldino, Salvatore; Pedro, José Ramón; Blay Llinares, Gonzalo

Aquest document és un/a article, creat/da en: 2014

Este documento está disponible también en : 10.1016/j.molcata.2014.01.006

A variety of iminopyridines were obtained by condensation of chiral amines with pyridine-2-carboxaldehyde and quinoline-8-carbaldehyde, or of aminoalkylpyridine derivatives with chiral ketones. These ligands were assessed in the enantioselective palladium catalyzed allylic substitutionof 1,3-diphenylprop-2-enyl acetate with dimethyl malonate affording the product dimethyl 1,3-diphenylprop-2-enylmalonate in good yields and moderate enantioselectivities (up to 62% ee). Catalytic activity and enantioselectivity were found to be highly dependent upon the steric properties of the ligands. The best enantioselectivity (62% ee) was obtained by an iminopyridine based on a camphane skeleton.

Veure al catàleg Trobes