Conflict of interest reporting in dentistry meta-analyses: a systematic review
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Beyari, Mohammed M.; Strain, Dan; Li, Chuan Silvia; Lamfon, Hanadi A.
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Aquest document és un/a article, creat/da en: 2014
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Objectives: The issue of reporting conflicts of interest (COI) in medical research has come under scrutiny over the
past decade. Absolute transparency is important when dealing with conflicts of interest to provide readers with all
essential information required to make an informative decision of the results. The key objective of this study was
to examine the prevalence of reporting conflicts of interest in therapeutic dental meta-analyses of Randomized
Control Trials (RCTs), and to investigate possible associations with other categorical variables.
Study Design: We conducted an extensive literature search across multiple databases to search for relevant review
articles for this study. We utilized pre-determined key words, and relied on three reviewers to test and review the
use of a data extraction form that was used for the meta-analyses. Data regarding study characteristics, direction of
results, and the significance of the results from each meta-analysis were extracted.
Results: There were 129 meta-analyses used in this review, and the reporting on conflict of interest was low with
only 50 (38.8%) of the articles possessing a conflict of interest statement (either confirming of denying COI). Of
these 50 articles, there were only 4 (8%) studies that reported an actual conflict of interest. A statement of conflicts
of interest was found in 29 (35.3%) of the papers that reported significant findings, whereas 35% of the papers that
reported positive results reported on conflict of interest. Prior to 2009, only 17 (25%) papers reported conflicts of
interest, but since 2009, 54.1% of papers collected had a conflict of interest statement.
Conclusions: Meta-analyses published in the field of dentistry do not routinely report author conflicts of interest.
Although few conflicts appear to exist, the field of dentistry should continue to ensure that best evidence reports
provide clear and transparent reporting of potential conflicts of interest in academic journals.
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