Information and Communication Technologies (ICTs) have become a key factor in the educational context, especially in the aftermath of the COVID-19 pandemic, and, correctly implemented, can help to improve academic performance. The aim of this research was to analyse the factors that influence teachers’ decisions to use ICT more- or less frequently to carry out tasks and exercises in their classes. To this end, we estimated a multilevel logistic model with census data from the individualized evaluation of students of the Community of Madrid (Spain) carried out at the end of the 2018–2019 academic year in primary and secondary education. Additionally, we applied multiple imputation techniques to deal with missing values. Based on our results, we found that motivated teachers who have received ICT training, teach calm and respectful classes, and work at schools where students have access to digital devices and frequently use ICT at home, have a high predisposition to use ICT in their classes. Considering our results, our recommendations are aimed at improving teacher training in ICT, encouraging a frequent but responsible use of ICT at home, and increasing the provision of technological resources in schools.