This study investigates the adoption of prevention measures inCroatia during the COVID-19 pandemic and its relationship withtourist behavior. The research adopts a mixed-method approachas it examines both practitioners’and tourists’viewpoints. A quali-tative study was conducted with eight destination service pro-viders, while the quantitative study took place among 333international tourists during their stay in the country. Results fromthe qualitative study show that the most frequently employed pre-vention measures are cleaning and disinfection of customer-usespaces, the use of hand sanitizers, mandatory face masks foremployees and guests, and social distancing. Tourism service pro-viders observed that international tourist behavior changed signifi-cantly from 2020 to 2021. Findings from the quantitative studyshow relatively high levels of perception of adoption of preventionmeasures among tourists, low levels of the perceived risk ofCOVID-19, and high levels of tourist satisfaction. Some differencesin tourist behavior related to gender and destination type are alsoobserved. Positive correlations are found between tourists’percep-tions of prevention measures and their satisfaction level, while thecorrelations between perceived risk of COVID-19 and preventionmeasures on one hand and perceived risk of COVID-19 and tou-rists’satisfaction on the other are found to be negative.